Volume-2 ,Issue-3, March-2026

Osteoarthritis (OA) is a long-term, degenerative joint disease that severely reduces quality of life. It is characterized by oxidative stress, inflammation, cartilage degradation, and chronic pain. Traditional pharmaceutical therapies alleviate symptoms, but they don't stop the progression of the disease and are frequently linked to negative side effects. The multi-targeted mechanisms of herbal medications, such as their anti-inflammatory, antioxidant, chondroprotective, analgesic, and immunomodulatory properties, have made them intriguing adjuncts or replacements. In preclinical and clinical trials, medicinal plants like Salix alba, Zingiber officinale, Withania somnifera, Boswellia serrata, and Curcuma longa have shown therapeutic value. Improvements in formulation techniques, such as standardized extracts and nano-based delivery systems, have improved clinical results and bioavailability. The phytoconstituents, modes of action, safety profiles, experimental and clinical data, formulation strategies, and regulatory issues of herbal treatments in the treatment of OA are all rigorously examined in this review. Future research should concentrate on large-scale clinical trials and individualized treatment plans. Combining evidence-based herbal remedies with traditional therapy may offer a comprehensive, patient-friendly approach.

Keyword: Osteoarthritis, Herbal Medicine, Phytoconstituents, Anti-Inflammatory, Chondroprotection, Natural Therapeutics, Complementary Therapy, Pain Management