Volume-2 ,Issue-3, March-2026

In India, Spondias pinnata grows in eastern Uttar Pradesh, Belgaum, Chikmagalur, Coorg, Hassan, Mysore, and Nasik, Pune, Raigad, Ratnagiri, and Thane. The plant has been utilized extensively in numerous traditional herbal remedies all over the world. Antimicrobial, antidiabetic, ulcer-protective, anticancer, antidiarrheal, anthelmintic, and hepatoprotective properties are reported to be present. There have also been reports of the plant's various parts being utilized as antitubercular, anti-emetic, and anti-thirst agents. Nevertheless, there is a lack of scientific research on the nephroprotective properties and acute toxicity of various leaf and bark extracts. As a result, an effort has been undertaken to investigate these pharmacological effects and identify the many phytoconstituent groups found throughout the entire plant. Methanolic, aqueous, and petroleum ether fractions will be extracted from the plant. The various extracts will be examined for cytotoxic and nephroprotective properties. The extracts will undergo preliminary phytochemical analyses to detect the presence of several phytoconstituents, which will then be isolated and characterized.

Keyword: Spondias pinnata, Nephroprotective, hepatoprotective, phytoconstituents ulcer-protective, anti-cancerous and herbal medicines